Be Careful with My Heart is a 2012 Philippine daytime television drama which premiered on ABS-CBN's PrimeTanghali noontime block from July 9, 2012 to November 28, 2014 airing before It's Showtime. It is also broadcast worldwide on The Filipino Channel. It is topbilled by Jodi Sta. Maria and Richard Yap. It is one of the most successful teleseryes of ABS-CBN. Due to its immense popularity and critical acclaim, albums, concerts, and worldwide tours were spawned. The show has been aired in regions of Africa, around Asia, the Middle East, and South America.

It is the fourth Philippine television series to be shot in high definition format after Rounin, Minsan Lang Kita Iibigin and Budoy.

After two successful years, it was first announced on the September 25, 2014 episode of TV Patrol that the series will air its final episode on November 28, 2014. In the Global Kapit-Bisig Day, the show simulcasted on TFC.tv during its last episode, followed by their live farewell broadcast. The Singing Bee and the re-run of hit Japanese anime series Princess Sarah was pre-empted to give way for the one-hour finale, airing from 11:15 am to 12:15 pm.