| CSU Research Output | Academic & Science |
| Contract Research Organisation | Academic & Science |
| Contract Research Organizations | Academic & Science |
| Cetos Research Organization (Bar Harbor, ME) | Academic & Science |
| Criterion Reference Objective | Academic & Science |
| Classes Reunion Organization | Academic & Science |
| Course Resources Online | Academic & Science |
| Clock Reference Oscillator (AT&T) | Academic & Science |
| Component Repair and Overhaul | Academic & Science |
| Center for Radiation Oncology | Academic & Science |
| Chromium(II) Oxide | Academic & Science |
| Container Release Order | Accounts and Finance |
| Corcoran (ca) | Airport Code |
| Civilian Repair Organisation | Associations & Organizations |
| Canceling Returns Only | Business |
| Consolidated Restaurant Operations | Business |
| Customer Relationship Optimization | Business |
| Customer Record Output | Business |
| Credited Retail Outlet | Business |
| Carded for Record Only | Business |
| Chief Research Officer | Business |
| Creon Resources, P.L.C. | Business |
| Conversion Rate Optimisation | Business |
| Costa Rican Outpost | Business |
| Company Relation Officer | Business |
| Cognizant Regional Office | Business |
| Codice di Riferimento dell'Operazione (Italian: bank money transfer) | Business |
| Certified Radio Operator | Business |
| Crown Pacific Partners, L. P. | Business |
| Competitor Relations Officer | Business |
| Crisis Response Operations | Community |
| Civil Rights Officer | Community |
| Character Relationships Objective | Community |
| Click Rate Optimization | Community |
| Church-Related Organization | Community |
| Club Race Officer | Community |
| Classique Rallye Organisation (French car club) | Community |
| Creative Roleplaying Organization (live action roleplaying games) | Community |
| Community Reuse Organization | Community |
| Community Relations Office | Community |
| Community Resource Officer | Community |
| Community Redevelopment Office | Community |
| Colorado Recorder Orchestra | Community |
| Cave Rescue Organization | Community |
| Chrono Revolution Omega | Computing |
| Conversion Rate Optimization | Computing |
| Crypto.com Coin | Cryptocurrency |
| Cathode Ray Oscilloscope | Electronics |
| Child Restoration Outreach | General |
| Customer Revenue Optimizer | General |
| Central Reservations Office | General |
| Corporate Reservations Office | General |
| Continuity Recheck Outgoing | General |
| Corporate Responsibility Officer | General |
| Chief Recognition Officer | General |
| Crisis Response Operation | General |
| Chapter Relations Office | General |
| Carbapenem Resistant Organisms | General |
| Complaints Resolution Official | General |
| Cessation of Regulated Operations | General |
| Cathode Ray Oscillograph | General |
| Control Room Operator | General |
| Chief Regulatory Officers | General |
| Conversation Rate Optimisation | General |
| Conversation Rate Optimization | General |
| Current Ray Oscillator | General |
| Construction Related Occupation | General |
| Change of Reporting Official | General |
| Coloured Roads Only | General |
| Car Rental Operator | General |
| Chief Range Officer | General |
| Cancel Rerouted Overflow | General |
| Central Reservation Office | Governmental |
| Counterfeit Resistant Option | Governmental |
| Criminal Records Office | Governmental |
| Contract Regulatory Organization | Governmental |
| Congressional Relations Officer | Governmental |
| Collection and Recycling Organisation | Governmental |
| Clinical Research Organization | Governmental |
| Columbia Recovery Office | Governmental |
| Community Rehabilitation Orders | Governmental |
| Combinatoire et Recherche Opérationnelle (French: Combinatorics and Operations Research) | International |
| Commonwealth Relations Office | International |
| Customer Relationship Officer | Jobs |
| Chief Revenue Officer | Jobs |
| Chief Requisition Offcier | Jobs |
| Complaint Resolution Official | Jobs |
| Chief Restructuring Officer | Jobs |
| Competitor Relations Officers | Jobs |
| Chief Risk Officer | Jobs |
| Chief Registration Officer | Jobs |
| Chief Returning Officer | Jobs |
| Center Rotate Offset | Maths |
| Clinical Research Office | Medical |
| Clinical Research Officer | Medical |
| Combat Rescue Officer | Military and Defence |
| Contract Research Organization | Military and Defence |
| Companies Registration Office | Regional |
| County Records Office | Regional |
| Centre Régional de l'Occasion (French: Regional Center of Opportunity) | Regional |
| Complaints Resolution Officer | Regional |
| Cave Rescue Organisation | Regional |
