The Lake Erie College of Osteopathic Medicine (LECOM) is a private graduate school of medicine, dentistry, and pharmacy with a main campus in Erie, Pennsylvania, and branch campuses in Greensburg, Pennsylvania, Bradenton, Florida, and Elmira, New York. Founded in 1992, LECOM confers medical (D.O.), dental (DMD), pharmacy (PharmD), as well as master's degrees in Health Services Administration, Biomedical Sciences, and Medical Education. LECOM operates one of the few accelerated three-year pharmacy programs in the country, and is one of 2 pharmacy schools in the country with a distance education program.

With over 2,200 enrolled medical students, the College of Osteopathic Medicine at LECOM is the largest medical school in the United States.

LECOM is accredited by the Middle States Commission on Higher Education, the American Osteopathic Association's Commission on Osteopathic College Accreditation, the Commission on Dental Accreditation, and the Accreditation Council for Pharmacy Education. The World Directory of Medical Schools lists LECOM's College of Osteopathic Medicine as a US medical school along with other accredited US MD and DO programs.