| Melbourne Dental Student Society | Academic & Science |
| Managerial Design Supplemental Service | Business |
| Marsoft Decision Support System | Business |
| Marketing Decision Support System | Business |
| Management Decision Support System | Business |
| Massive Data Storage Service | Computing |
| Massive Data Storage System | Computing |
| Mass Data Storage System | Computing |
| Mobile Display Sub System | Computing |
| Multi Dynamic Sound System | Computing |
| Mobile Data Synchronization Service | Computing |
| Multicast Distributed Shortcut Switching | Computing |
| Marbach Die Storage System | General |
| Ma Dou So Shi | General |
| Mean Deviation Similarity Score | General |
| Measured Depth Sub Sea | General |
| Multiple Disconnect Safety Systems | General |
| Multi Drive Slice Service | General |
| Maintenance Decision Support Systems | General |
| Madras Delayed Standard Specifications | General |
| Mitsubishi Dynamic Suspension System | General |
| Mobilization Decision Support System | Governmental |
| Maintenance Decision Support System | Governmental |
| Missouri Department of Social Services | Governmental |
| II Marine Air-Ground Task Force (MAGTF) Deployment Support System II | Governmental |
| Medical Device Safety Service | Medical |
| Medical Decision Support System | Medical |
| Medical Data Surveillance System | Medical |
| Michigan Disease Surveillance System | Medical |
| Medical Decision Support Software | Medical |
