The United States District Court for the Northern District of New York (in case citations, N.D.N.Y.) serves one of the 94 judicial districts in the United States and one of four in the state of New York. The Interim U.S. Attorney for the district is Antoinette T. Bacon since September 2, 2020. Appeals from the Northern District of New York are taken to the United States Court of Appeals for the Second Circuit, which has jurisdiction over the four districts of New York, the District of Connecticut and the District of Vermont (except for patent claims and claims against the U.S. government under the Tucker Act, which are appealed to the Federal Circuit).

Its jurisdiction comprises the counties of Albany, Broome, Cayuga, Chenango, Clinton, Columbia, Cortland, Delaware, Essex, Franklin, Fulton, Greene, Hamilton, Herkimer, Jefferson, Lewis, Madison, Montgomery, Oneida, Onondaga, Oswego, Otsego, Rensselaer, Saratoga, Schenectady, Schoharie, St. Lawrence, Tioga, Tompkins, Ulster, Warren, and Washington.

The court has offices in Albany, Binghamton, Plattsburgh, Syracuse, and Utica. The court also holds court at facilities in Watertown. The court accepts filings from members of the bar through an automated case management system CM/ECF over the Internet.