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Answer» What is Nothing by mouth mean? Nothing by mouth is a medical instruction meaning to withhold food and fluids. It is also known as nil per os (npo or NPO), a Latin phrase that translates literally to English as "nothing through the mouth". Variants include nil by mouth (NBM), nihil/non/nulla per os, or complete bowel rest. A liquid-only diet may also be referred to as bowel rest. NPO is one of the abbreviations that is not used in AMA style; "nothing by mouth" is spelled out instead. reference
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