| Society Of Cosmetic Chemists | Academic & Science |
| Source Capital Corporation | Business |
| Synthetic Organic Chemistry Core | Chemistry |
| Seymour Osman Community Center | Community |
| Santiam Outreach Community Center | Community |
| Strengthening Our Christian Community | Community |
| Sherwood Oaks Christian Church | Community |
| Students of Color Conference | Community |
| Scholars Of Color Conference | Community |
| School Of Cadet Command | Community |
| Sarov Open Computing Center | Computing |
| Symposium on Cloud Computing | Computing |
| Suggested Optical Cable Code | Computing |
| State of Ohio Computing Center | Computing |
| SocialCoin | Cryptocurrency |
| Southwestern Oregon Community College | Educational Institute |
| Sounds of Colorado College | Educational Institute |
| Sales And Operations Cost Calculator | General |
| Strengthening Our Capacity To Care | General |
| State Officers Compensation Commission | General |
| Section On Critical Care | General |
| Second Order Cone Cut | General |
| Security Operations Control Center | General |
| Submarine Operational Command Center | General |
| Special Operations Compatible Carbine | General |
| Sherman Oaks Collective Care | General |
| Singer Owners Car Club | General |
| Students of Color Coalition | General |
| Students of Colour Collective | General |
| Standard Optical Cable Code | General |
| SMS Originated Call Control | General |
| Store Operated Calcium Channel | General |
| Strategic Operational Command Center | General |
| Synchronized Operations Command Center | General |
| Soil Organic Carbon Content | General |
| Switching Office Control Center | General |
| Special Operations Command Central | General |
| Source Optimized Channel Code | General |
| Simulations Operations Control Center | General |
| SFU Opinion and Comments Corpus | General |
| System Operations Control Center | Governmental |
| Solidaridad Obrera Cristiana de Cataluña | International |
| Selly Oak Commissioning Consortium | Medical |
| Sector Operations Control Center (norad) | Military and Defence |
| South Orange County California | Regional |
| Satellite Operations Control Center | Space Science |
| Soccer | Sports |
