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INFO: Full form for MTD is Maximum Therapeutic Dose in Medical category
MTD also has other full forms in other categories mentioned below.

INFO: Full form for MTD is Maximum Therapeutic Dosage in Medical category
MTD also has other full forms in other categories mentioned below.

INFO: Full form for MTD is Minimum Therapeutic Dosage in Medical category
MTD also has other full forms in other categories mentioned below.

Methadone, sold under the brand names Dolophine and Methadose among others, is a synthetic opioid agonist used for opioid maintenance therapy in opioid dependence and for chronic pain management. Detoxification using methadone can be accomplished in less than a month, or it may be done gradually over as long as six months. While a single dose has a rapid effect, maximum effect can take up to five days of use. The pain-relieving effects last about six hours after a single dose. After long-term use, in people with normal liver function, effects last 8 to 36 hours. Methadone is usually taken by mouth and rarely by injection into a muscle or vein.

Side effects are similar to those of other opioids. These frequently includes dizziness, sleepiness, vomiting, and sweating. Serious risks include opioid abuse and respiratory depression. Abnormal heart rhythms may also occur due to a prolonged QT interval. The number of deaths in the United States involving methadone poisoning declined from 4,418 in 2011 to 3,300 in 2015. Risks are greater with higher doses. Methadone is made by chemical synthesis and acts on opioid receptors.

Methadone was developed in Germany around 1937 to 1939 by Gustav Ehrhart and Max Bockmühl. It was approved for use in the United States in 1947. It is on the World Health Organization's List of Essential Medicines. In 2013, about 41,400 kilograms were manufactured globally. It is regulated similarly to other narcotic drugs. It is not particularly expensive in the United States.

INFO: Full form for MTD is Maximum Tolerated Dose in Medical category
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INFO: Full form for MTD is Mycobacterium Tuberculosis Direct in Medical category
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Hippocampal sclerosis (HS) is a neuropathological condition with severe neuronal cell loss and gliosis in the hippocampus, specifically in the CA-1 (Cornu Ammonis area 1) and subiculum of the hippocampus. It was first described in 1880 by Wilhelm Sommer. Hippocampal sclerosis is a frequent pathologic finding in community-based dementia. Hippocampal sclerosis can be detected with autopsy or MRI. In MRI, a decrease in signal is observed at T1 and an increase in signal at T2. Positron emission tomography is also used as an aid for diagnosis. In PET examination, glucose uptake is lower than in the normal part. The reason for this is that the sclerotic part works at a lower level than the normal part and needs less energy. Individuals with hippocampal sclerosis have similar initial symptoms and rates of dementia progression to those with Alzheimer's disease (AD) and therefore are frequently misclassified as having Alzheimer's Disease. But clinical and pathologic findings suggest that hippocampal sclerosis has characteristics of a progressive disorder although the underlying cause remains elusive.A diagnosis of hippocampal sclerosis has a significant effect on the life of patients because of the notable mortality, morbidity and social impact related to epilepsy, as well as side effects associated with antiepileptic treatments.

INFO: Full form for MTS is Muir–Torre Syndrome in Medical category
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INFO: Full form for MTS is Mohr-Tranebjaerg Syndrome in Medical category
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INFO: Full form for MTS is Maladies Transmises Sexuellement in Medical category
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INFO: Full form for MTS is Mitochondrial Targeting Sequence in Medical category
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INFO: Full form for MTS is Microneedle Therapy System in Medical category
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