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INFO: Full form for PRP is Polyribosyl Ribitol Phosphate in Medical category
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INFO: Full form for ULS is Under Larry’s Scrotum in Medical category
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INFO: Full form for PRE is Progesterone Response Element in Medical category
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INFO: Full form for PRE is Progressive Resistance Exercise in Medical category
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INFO: Full form for UIP is Unconventional Innovations Program in Medical category
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INFO: Full form for UIP is Undegradable Intake Protein in Medical category
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INFO: Full form for UIP is University of Iowa Physicians in Medical category
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INFO: Full form for CPX is Complete Physical eXamination in Medical category
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INFO: Full form for BPN is Brevard Physicians Network in Medical category
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INFO: Full form for BPN is Brachial Plexus Neuropathy in Medical category
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INFO: Full form for NEF is Nurses Educational Funds in Medical category
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INFO: Full form for NEF is Negative Early Factor in Medical category
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Uroguanylin is a 16 amino acid peptide that is secreted by enterochromaffin cells in the duodenum and proximal small intestine. Guanylin acts as an agonist of the guanylyl cyclase receptor guanylate cyclase 2C (GC-C), and regulates electrolyte and water transport in intestinal and renal epithelia. Its sequence is H-Asn-Asp-Asp-Cys(1)-Glu-Leu-Cys(2)-Val-Asn-Val-Ala-Cys(1)-Thr-Gly-Cys(2)-Leu-OH.

In humans, the uroguanylin peptide is encoded by the GUCA2B gene. Uroguanylin may be involved in appetite and perceptions of 'fullness' after eating meals, as suggested by a study into mice.

INFO: Full form for BLL is Blood Lead Level in Medical category
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INFO: Full form for BLL is Bilingual Language Laboratory in Medical category
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INFO: Full form for SCK is Semi Constrained Knee in Medical category
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INFO: Full form for PoO is Polonium Monoxide in Medical category
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INFO: Full form for BPD is Bi-Parietal Diameter in Medical category
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INFO: Full form for BPD is Body Part Discomfort in Medical category
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Borderline personality disorder (BPD), also known as emotionally unstable personality disorder (EUPD), is a personality disorder characterized by a long-term pattern of unstable interpersonal relationships, distorted sense of self, and strong emotional reactions. Those affected often engage in self-harm and other dangerous behaviors, often due to their difficulty with returning their emotional level to a healthy or normal baseline. They may also struggle with a feeling of emptiness, fear of abandonment, and detachment from reality. Symptoms of BPD may be triggered by events considered normal to others. BPD typically begins by early adulthood and occurs across a variety of situations. Substance use disorders, depression, and eating disorders are commonly associated with BPD. Approximately 10% of people affected with the disorder die by suicide. The disorder is often stigmatized in both the media and the psychiatric field and as a result is often underdiagnosed.

The causes of BPD are unclear but seem to involve genetic, neurological, environmental, and social factors. It occurs about five times more often in a person who has an affected close relative. Adverse life events appear to also play a role. The underlying mechanism appears to involve the frontolimbic network of neurons. BPD is recognized by the Diagnostic and Statistical Manual of Mental Disorders (DSM) as a personality disorder, along with nine other such disorders. The condition must be differentiated from an identity problem or substance use disorders, among other possibilities.

BPD is typically treated with psychotherapy, such as cognitive behavioral therapy (CBT) or dialectical behavior therapy (DBT). DBT may reduce the risk of suicide in the disorder. Therapy for BPD can occur one-on-one or in a group. While medications cannot cure BPD, they may be used to help with the associated symptoms. Despite no evidence of their effectiveness, SSRI antidepressants and quetiapine remain widely prescribed for the condition. Severe cases of the disorder may require hospital care.

About 1.6% of people have BPD in a given year, with some estimates as high as 6%. Women are diagnosed about three times as often as men. The disorder appears to become less common among older people. Up to half of those with BPD improve over a ten-year period. Those affected typically use a high amount of healthcare resources. There is an ongoing debate about the naming of the disorder, especially the suitability of the word borderline.

INFO: Full form for BPD is Balanced Placebo Design in Medical category
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INFO: Full form for BPD is Bilio-Pancreatic Diversion in Medical category
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INFO: Full form for BPD is Billio-Pancreatic Diversion in Medical category
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INFO: Full form for TVF is Team, Vision, Future in Medical category
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The Undiagnosed Diseases Network (UDN) is a research study that is funded by the National Institutes of Health Common Fund. Its purpose is to bring together clinical and research experts from across the United States to solve the most challenging medical mysteries using advanced technologies.

UDN was established in 2014 with seven clinical sites located at medical institutions across the United States. As of 2019, twelve clinical sites are open. Shared resources include a central biorepository, sequencing core, metabolomics core, and animal research centers.

INFO: Full form for BOW is Bag Of Waters in Medical category
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INFO: Full form for CRD is Cysteine-Rich Domain in Medical category
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INFO: Full form for CRD is Chronic Renal Disease in Medical category
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INFO: Full form for CRD is Carbohydrate Recognition Domain in Medical category
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INFO: Full form for CRD is Central Respiratory Drive in Medical category
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The Centre for Reviews and Dissemination (CRD) is a health services research centre based at the University of York, England. CRD was established in January 1994, and aims to provide research-based information for evidence-based medicine. CRD carries out systematic reviews and meta-analyses of healthcare interventions, and disseminates the results of research to decision-makers in the NHS.

CRD produces three databases:

These are freely available from the CRD database website [1] and as part of the Cochrane Library.

CRD also publishes a number of regular reports including Effective Health Care and Effectiveness Matters.

CRD is funded by the UK Department of Health's NHS Research and Development Programme, as well as from a number of other sources.